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New Venegis XR 75 Mg Extended Release 28 Capsules ingredient Venlafaxine HCl View larger

Venegis XR 75 Mg Extended Release 28 Capsules ingredient Venlafaxine HCl

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Venegis XR 75 Mg Extended Release 28 Capsules ingredient Venlafaxine HCl

VENEGIS XR 75 mg extended release hard capsule
It is taken orally.
Active ingredient: Each capsule contains 84.84 mg venlafaxine hydrochloride equivalent to 75 mg venlafaxine.

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Auxiliary substances: Microcrystalline cellulose, sodium chloride, ethylcellulose, talc, dimethicone, potassium chloride, copovidone, anhydrous colloidal silica, xanthan gum, yellow iron oxide, red iron oxide, titanium dioxide, gelatin.
You should read this USE INSTRUCTION carefully before you start using this medicine, because it contains important information for you.
 
Save these instructions for use. You can need to read again.
 
If you have other questions, please talk your doctor or pharmacist.
 
This medicine has been prescribed for you personally, do not give it to others.
 
When using this medicine, tell the doctor or your doctor if you go to the hospital that you are using this medicine.

 
We sleep exactly as written in this instruction. Do not use high or low doses other than the recommended dose for the medication.

In this Instructions for Use:
1. What is VENEGIS XR and what is it used for?
2. Things to watch out for before using VENEGIS XR
3. How to use VENEGIS XR
4. What are the possible side effects?
5. Storage of VENEGIS XR
Their headlines are in place.

1. What is VENEGIS XR and what is it used for?
 
The extended release micropellet is in the form of a capsule. An antidepressant belonging to the drug group called serotonin and noradrenalin reuptake inhibitors (SNRIs).
 
They are blister packs containing 28 micropellets capsules in Kut.
 
It is used in the treatment of major depression, in the treatment of panic disorder with or without agoraphobia, with recurrent major depression and new episodes (epilepsy), generalized anxiety disorder (GAD) treatment, social phobia treatment, agoraphobia (where the patient feels panic attacks may occur).

2. Things to watch out for before using VENEGIS XR
Major Depression and other psychiatric disorders in children and adolescents who made short-term clinical trials of antidepressants, suicidal thinking and behavior (suicide predisposition) increased the risk. When considering the use of VENEGIS XR or any other antidepressant in children or adolescents, the identified risk and clinical need should be balanced. See the warning about suicide.
The use of antidepressants in children and young people up to the age of 24 is likely to increase suicidal thoughts or behavior. Therefore, especially in the beginning and in the first months of treatment, increasing the drug dose / reduction or discontinuation period of unrest in it can show the patient, hyperactivity, such as unexpected changes in behavior or family need of the patient for reasons such as the possibility of suicide need to be monitored closely by both therapeutics.
VENEGIS XR is not approved for use in pediatric patients (under the age of 18).
DO NOT USE VENEGIS XR in the following situations
 
If you have any allergies to venlafaxine or any of the ingredients in the formula.
 
With drugs called monoamine oxidase inhibitors (MAOI): You should not start treatment with venlafaxine at least 14 days after discontinuation of MAOI therapy. You should stop using venlafaxine at least 7 days before starting any MAOI use.
VENEGIS XR CAREFULLY USE THE FOLLOWING

If,
 
If another drug is used concurrently with VENEGIS XR, serotonin syndrome or a Neuroleptic Malign Syndrome (NMS) -like reaction may increase the risk of development (see section "Use with other medicines").
Increased risk of bone fracture has been reported in patients using drugs of the serotonin reuptake inhibitor class, including VENEGIS XR. The reason for this increase is not fully known.

 
If you have eye problems such as some glaucoma (pressure increase in the eye).
 
If you have high blood pressure history.
 
If you have a history of heart problems.
Diagnosed or suspected congenital prolonged QT syndrome (a severe arrhythmias that can cause sudden death and heart condition) or torsades de pointes (life-threatening irregular heart beat) should be avoided in patients.

If you have a seizure (convulsion) background.
 
If you are using medications known as "diuretics" that lose water to your body, or if your body has lost water due to any reason.
 
If you have easy bruising on your skin or if you tend to bleed easily (history of bleeding disorders) or if you are using another medication that increases the risk of bleeding.
 
If your cholesterol level is high.
 
If you have a history of bipolar disorder (bipolar disorder) or if you have bipolar disorder history in one person in your family.
 
If you have aggressive behavior history.
 
If you have substance abuse and dependency history.
 
If you are using an attenuating medication.
Please consult your doctor if these warnings apply to you, even at any time in the past.

Suicidal thoughts and worsening of depression or anxiety disorders
If you are experiencing a psychological depression (you are depressed) or if you have certain anxiety disorders, you may have the idea of ​​killing yourself from time to time. These considerations may increase if you start using antidepressants first or if there is any change in the total dose or dosage frequency. Information obtained from clinical trials has shown that antidepressant drugs increase the risk of suicidal tendency in children, adolescents and young adults (18-24 years) with major depression and other psychiatric disorders.
If you have ever thought of harming or killing yourself at any time, contact your doctor immediately or go to a hospital.
Whether you are a depressed or an anxiety disorder member of a clan or a close friend, and you do not want them to read this instruction manual will help you. Tell them to report if they feel that depression or anxiety is getting worse or if they are worried about any changes in your behavior.

Use in children and adolescents under the age of 18
VENEGIS XR is not normally used in children and adolescents under 18 years of age. In addition, you should be aware that patients under the age of 18 use side effects when they use this class of medications, such as hostility, suicidal thoughts, and self-harm.
Use of VENEGIS XR with food and beverage
You should buy VENEGIS XR with food (see section 3, named "How to use VENEGIS XR").
You should avoid taking alcohol for as long as you use VENEGIS XR.

Pregnancy
Consult your doctor or pharmacist before using this medication.
If you are pregnant or are trying to conceive, tell your doctor about it. You should only use VENEGIS XR if you think it is more than the risk of your potential benefits with your doctor.
If you use VENEGIS XR during pregnancy, please allow your doctor or your ejaculation to know that your baby has some indication when she is born. These symptoms usually occur after the birth of the baby. Symptoms include the inability to feed properly and to breathe properly. If you have these symptoms when you are born, or if you are worried that you may be, contact your doctor and / or your e-mail.
If you notice that you are pregnant during your treatment, consult your doctor or pharmacist immediately.

Breast-feeding
Consult your doctor or pharmacist before using this medication.
The VENEGIS XR has passed. There is a risk of creating an effect on the baby. So you should discuss this with your doctor, your doctor will decide whether you should stop sucking or should you use VENEGIS XR.

Vehicle and machine use
Do not use cars and any machinery until you understand how VENEGIS XR is affecting you.
Important information about some of the ancillary substances in the content of VENEGIS XR
Each capsule contains 18.104 mg of sodium (as sodium chloride). This should be considered for patients on a controlled sodium diet.
Use with other medicines
 
Do not use VENEGIS XR if you are on medication known as MAOI or if you have used it in the last 14 days.

 
As a potentially life-threatening condition (see "Possible side effects" section) "serotonin syndrome" may occur when taken with other serotonergic drugs, especially when treated with venlafaxine. Examples of these drugs include:
 Triptans (used for migraine)
 Medications used to treat mood disorders such as SNRIs, selective serotonin reuptake inhibitors (SSRIs), or other medications that contain lithium.

o Medicines known as MAOI, such as linezolid, an antibiotic (used in the treatment of infections), and methylene blue
o Medications containing sibutramine (used to lose weight)
o St. Products containing John's Wort (a natural or herbal medicine used in the treatment of mild depression, also called Hypericum perforatum)
o Serotonin precursors such as tryptophan
o Very strong painkillers such as fentanyl and its derivatives, tramadol, meperidine, tapentadol, metadone, pentazocine
o Dextromethorphan (a drug used in the treatment of cough)
Serotonin syndrome may include a combination of the following:
Discomfort, hallucinations, loss of coordination, rapid heart rate, increased body temperature, rapid changes in blood pressure, increased reflexes, diarrhea, coma, nausea, vomiting. If you think that serotonin syndrome has come to fruition, you will receive immediate medical support.
In addition, the following medicines may interact with VENEGIS XR and should be used with caution. It is especially important that you talk to your doctor or pharmacist if you are using any of the following medicines:
 
Ketoconazole (an antifungal drug)
 
Haloperidol (to treat psychiatric disorders)
 
Metoprolol (a drug that treats high blood pressure and heart problems)
Please inform your doctor or pharmacist if you are using or have recently used any medicine with or without a prescription.

3. How to use VENEGIS XR
 
Instructions for proper use and dose / application frequency:
The recommended starting dose in the major depression is 75 mg VENEGIS XR per day. Patients who do not respond to an initial daily dose of 75 mg may benefit from doses of up to 375 mg per day. The recommended initial dose for generalized anxiety disorder is 75 mg VENEGIS XR per day. Patients who do not respond to an initial daily dose of 75 mg may benefit from a maximum dose of 225 mg per day. The recommended dose of social phobia is 75 mg VENEGIS XR daily. There is no evidence that higher doses provide additional benefit. However, in patients who do not respond to an initial daily dose of 75 mg, the dose may be increased to a maximum of 225 mg per day. The recommended dose for panic disorder is 37.5 mg VENEGIS XR once daily for the first 7 days. The dose should then be increased to 75 mg per day. Patients who do not respond to 75 mg daily doza may benefit from a maximum dose of 225 mg per day.

Dose increments should be made at intervals of about 2 weeks or more, but not at shorter intervals of 4 days.

 
Application path and method:
It is recommended to take VENEGIS XR with food. Each capsule should be swallowed whole as liquid. The capsule should not be divided, crushed, chewed or mixed with water. VENEGIS XR should be taken once a day and roughly the same hours (morning or evening).
 
Different age groups:

Use in children:
Children under the age of 18 years do not have sufficient experience related to the use of venlafaxine.

Use in the elderly:
In elderly patients, it is not advisable to adjust in usual doses only because of their age.

 
Special use cases:
Kidney and liver failure:
Patients with renal and / or liver failure should take low doses of venlafaxine. If you have a liver or kidney problem, tell your doctor. Because your VENEGIS XR dose may need to be reduced.
If you have an impression that the effect of VENEGIS XR is too strong or weak, talk to your doctor or pharmacist.
If you use more VENEGIS XR than you need:
A possible overdosage indication may include rapid heart rate, change in awake level (ranging from sleepiness to coma), growth in pupils, seizures or crises, and vomiting.
Published retrospective studies indicate that venlafaxine leads to more deaths than antidepressants in the SSRI group, less than the "tricyclic" group antidepressants. Studies showing the frequency, distribution and causes of the disease show that the patients treated with venlafaxine have a higher risk of suicide than those treated with antidepressants. It is not clear how much of the overdose related deaths depend on the toxicity of venlafaxine, and how many of the other properties of patients receiving venlafaxine.

If you use more than you need from VENEGIS XR, talk to a doctor or pharmacist.


If you forget to use VENEGIS XR:
Do not take double doses to compensate for forgotten doses
.

Effects that may occur when treatment with VENEGIS XR is terminated:

Even if you feel better, do not stop your treatment or reduce your desire without your doctor's advice. If your doctor thinks you do not need to use VENEGIS XR anymore, he can tell you to slowly decrease your dose before he or she interrupts the treatment altogether. It should be known that side effects will occur when the use of VENEGIS XR is discontinued in humans, especially when VENEGIS XR is abruptly stopped or when the dose is reduced too quickly. In some patients there is a feeling of tiredness, dizziness, dizziness, headache, insomnia, nightmares, lack of appetite, nausea, diarrhea, irritability, agitation, confusion, ringing in the ears, tingling, weakness, sweating, seizure or flu-like symptoms were observed.
Your doctor will advise you on how to gradually stop VENEGIS XR treatment. If you observe any of these and other symptoms yourself, consult your doctor for further advice.

4. What are the possible side effects?
As with all medicines, there may be side effects in people sensitive to substances in the VENEGIS XR.
If you have one of the following, stop using VENEGIS XR and report it to your doctor or contact your nearest hospital emergency department:
 
Sudden hypersensitivity reactions, nervous or anxious feelings, dizziness, palpitations, sudden reddening and / or irritability may occur due to a severe response to substances allergic to the body such as tightness, wheezing, swallowing or breathing difficulties, facial throat, or feeling of warmth
 
Severe rash, itching or hives (usually skin rash with red or pale stains, with itching)
 
Signs and symptoms of serotonin syndrome which include symptoms such as drowsiness, hallucinations, loss of coordination, rapid heart rate, increase in body temperature, rapid changes in blood pressure, overactive reflexes, diarrhea, coma, nausea and vomiting
The most serious form of serotonin syndrome is called Neuroleptic Malign Syndrome (NMS). NMS indications may include such symptoms as fever, increased heart rate, sweating, severe muscle stiffness, confusion, elevation of muscle enzymes (determined by blood testing).

Other side effects you should tell your doctor about:
 
Coughing, wheezing, breathlessness and high temperature
 
Blood in black stool or stool
 
Liver inflammation (hepatitis) may be indicated in skin color or in the eyes with yellowing, itching or dark urine
 
Heart problems such as rapid or irregular heartbeat, elevated blood pressure
 
Eye problems such as eye enlargement, blurred vision
 
Problems related to nerves such as dizziness, tingling, movement disorder, seizure or crisis
 
Psychiatric problems such as hyperactivity and euphoria (feeling uneasily excited)
 
Effects that may occur when treatment is terminated (see how to use VENEGİS XR, effects that may occur when treatment with VENEGİS XR is terminated)
Do not worry if you see small white pellets and granules in your stomach after using this medicine. VENEGİS XR capsules contain small white balls called venlafaxine, called spheroids. These spheroids are released from within the capsules. Venlafaxine, which is present on your back in your bowel and in your intestines, is slowly released. The shell of the spheroids is insoluble and exudates. For this reason, even if you have spheroids in your stomach, your drug dose has been absorbed.

 List of all undesirable effects:
 Very common side effects (May affect more than 1 person in 10 people)
 
Headache, dry mouth, sweating (including night sweats)
 
Nausea
 Widespread side effects (may affect 1 to 10 people per 100 people)
 
Weight loss, decreased appetite, constipation, vomiting, increased cholesterol
 
Feeling of rupture from self and reality, nervousness, confusion, abnormal dreams, insomnia
 
Shivering, increased muscle tone
 
Tingle
 
Increased blood pressure, skin flushes, palpitation
 
Increase in urination, difficulty in urination
 
Decreased sexual desire, abnormal ejaculation / orgasm (in men), lack of orgasm, erectile dysfunction
 
Menstrual irregularities such as an increase in bleeding or an increase in irregular bleeding
 
Weakness (asthenia), dizziness, drowsiness, chills
 
Blurred vision

Stretch
 
Fatigue, fatigue
 
chill
Uncommon (may affect 1-10 people per 1000 people)
 
Bruising, black stools or stools that may be signs of internal bleeding
 
Gnashing of teeth, involuntary movement of muscles
 
hallucinations
 
Blistering and / or itchy rash, especially in face, mouth, tongue, throat area or hands and feet
 
Sensitivity to sunlight, abnormal hair loss, rash
 
Coordination and balance impairment, drowsiness (particularly when the leg is very fast), fainting, rapid heart rate
 
Weight gain, diarrhea
 
Change in taste perception
Decrease in feelings and feelings, agitation (tension)
Tinnitus in the ears
Can not go on
 
Abnormal orgasm (women)
 
Dyspnea (shortness of breath, difficulty in breathing)
Sparse (every 10 000 people can affect 1-10 people)
 
Feeling of not feeling well or not standing or standing; seizure or crisis, extreme excitement or euphoria (excessive emotion such as joy, trust, strength)
 
I can not control an udder
Fertility is unknown (not available at any given time)
 
Decrease in the amount of tormbocytes in your body can lead to increased risk of injury or bleeding; blood disorders that can lead to an increased risk of infection, slight alteration in the amounts of the liver enzymes, reduction in the level of sodium in the blood
 
Itching, deep or yellowing of the eyes, dark urine or cold may be indicative of inflammation in the liver (hepatitis)
Excessive fluid intake (inappropriate ADH syndrome)
 
Abnormal milk production from breasts
 
Whether you experience high fever, confusion or tension and sweating, or irregular muscle movements that you can not control with hardness in your muscles, this can be a sign of a serious condition called neuroleptic malignant syndrome
 
Serotonin syndrome such as over-excited feeling, numbness, rapid eye movements, clumsiness, lack of fit, intoxication, sweating, muscle stiffness
 
Confusion and disorientation (delirium) with hallucinations
 
Stiffness, spasm or involuntary movements in the muscles
 
The thought of self-harm or killing
 
Serious eye pain and decreased vision or blur
 
Drop in blood pressure to cause fainting, abnormal, rapid or irregular heartbeat
 
Increased amount of white blood cells (pulmonary esophagus) with an inflammatory lung disease such as coughing, wheezing, cut breathing and high fever
 
Severe and abnormal back pain (may indicate serious problems in the intestine, liver or pancreas)
 
Skin rash that can lead to severe rash, itching, mild severe rash
 
Unexplained muscle pain, sensitivity or weakness
 
Swelling on the face and on the stomach, difficulty breathing or breathing, usually rash (a serious allergic reaction)
 
Confusion
 
Vertigo (vertigo-induced dizziness)
 
Irritability
 
Bone fracture

Stretch
 
Fatigue, fatigue
 
chill
Uncommon (may affect 1-10 people per 1000 people)
 
Bruising, black stools or stools that may be signs of internal bleeding
 
Gnashing of teeth, involuntary movement of muscles
 
hallucinations
 
Blistering and / or itchy rash, especially in face, mouth, tongue, throat area or hands and feet
 
Sensitivity to sunlight, abnormal hair loss, rash
 
Coordination and balance impairment, drowsiness (particularly when the leg is very fast), fainting, rapid heart rate
 
Weight gain, diarrhea
 
Change in taste perception
Decrease in feelings and feelings, agitation (tension)
Tinnitus in the ears
Can not go on
 
Abnormal orgasm (women)
 
Dyspnea (shortness of breath, difficulty in breathing)
Sparse (every 10 000 people can affect 1-10 people)
 
Feeling of not feeling well or not standing or standing; seizure or crisis, extreme excitement or euphoria (excessive emotion such as joy, trust, strength)
 
I can not control an udder
Fertility is unknown (not available at any given time)
 
Decrease in the amount of tormbocytes in your body can lead to increased risk of injury or bleeding; blood disorders that can lead to an increased risk of infection, slight alteration in the amounts of the liver enzymes, reduction in the level of sodium in the blood
 
Itching, deep or yellowing of the eyes, dark urine or cold may be indicative of inflammation in the liver (hepatitis)
Excessive fluid intake (inappropriate ADH syndrome)
 
Abnormal milk production from breasts
 
Whether you experience high fever, confusion or tension and sweating, or irregular muscle movements that you can not control with hardness in your muscles, this can be a sign of a serious condition called neuroleptic malignant syndrome
 
Serotonin syndrome such as over-excited feeling, numbness, rapid eye movements, clumsiness, lack of fit, intoxication, sweating, muscle stiffness
 
Confusion and disorientation (delirium) with hallucinations
 
Stiffness, spasm or involuntary movements in the muscles
 
The thought of self-harm or killing
 
Serious eye pain and decreased vision or blur
 
Drop in blood pressure to cause fainting, abnormal, rapid or irregular heartbeat
 
Increased amount of white blood cells (pulmonary esophagus) with an inflammatory lung disease such as coughing, wheezing, cut breathing and high fever
 
Severe and abnormal back pain (may indicate serious problems in the intestine, liver or pancreas)
 
Skin rash that can lead to severe rash, itching, mild severe rash
 
Unexplained muscle pain, sensitivity or weakness
 
Swelling on the face and on the stomach, difficulty breathing or breathing, usually rash (a serious allergic reaction)
 
Confusion
 
Vertigo (vertigo-induced dizziness)
 
Irritability
 
Bone fracture

VENEGİS XR can sometimes cause undesirable side effects. These side effects include increased blood pressure or abnormal heart rate, changes in blood parameters or slight changes in liver enzymes, sodium and cholesterol levels. More rarely, VENEGİS XR can increase the risk of bleeding and injury by reducing the number of platelets in your bloodstream. For this reason, your doctor may require a blood test, especially if you use VENEGİS XR, which is long-lasting.
If you encounter any side effects not mentioned in these instructions for use, please inform your doctor or pharmacist.

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